Glucose EAQs Practice Test 2026 - Free Glucose EAQs Practice Questions and Study Guide

When extracellular fluid becomes hyperosmolar, water moves out of the cells to the higher-osmolality outside to balance the osmotic gradient. In type 1 diabetes, elevated blood glucose raises extracellular osmolality, so water shifts from the intracellular space into the intravascular (plasma) compartment. This makes the inside of cells shrink while the plasma becomes relatively more concentrated. So, the observed direction is from intracellular to intravascular driven by hyperosmolarity.